Constitutive activation of Akt promotes senescence in a variety of cell types [16], including endothelial progenitors, mouse embryonic fibroblasts [59]C[61] and mouse prostate epithelial cell [60] and links diet-induced obesity with vascular senescence and cardiovascular disease [62]

Constitutive activation of Akt promotes senescence in a variety of cell types [16], including endothelial progenitors, mouse embryonic fibroblasts [59]C[61] and mouse prostate epithelial cell […]

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